We have a Teledyne FLIR A655sc camera for highly resolved thermal imaging, which allows for non-invasive temperature mapping of tissue. This enables direct feedback of the potentially damaging effects of absorbing too much laser light, which is important for setting guidelines for safe clinical implementation of PAI.

Thermal imaging is also useful as a complementary monitoring system for a range of other studies where perfusion and oxygen saturation is being studied, such as in reconstructive surgery, since temperature affects perfusion, which in turn alters oxygen saturation. Furthermore, we use thermography to study the effect of cryotherapy of tumors.

Our camera is capable of capturing images with a sub-Kelvin thermal resolution, a spatial resolution of 24 µm and at a maximum frame rate of 200 fps.