Machine learning detection of tumor genes from epigenetic data
A deep learning method is proposed for detecting tumor genes based on their unique combined epigenetic signatures. Large volumes of epigenetic data will be processed by the Tomoiaga group at Manhattan College and Columbia. This data will be utilized to train and validate deep network models capable of accurately detecting epigenetic patterns, which can then be leveraged for the classification of genes as tumor, tumor suppressor, or non-tumor. A key advantage of this approach is its applicability across various tissue and tumor types, allowing for the identification of new tumor genes, even in rare cancers.
Selected publications