Malin Malmsjö
Professor
Cryosurgery of eyelid actinic keratosis and the effect of adrenaline in local anesthetics - temperature mapping using IR thermography
Author
Summary, in English
The efficacy of cryosurgery is believed to depend on the thaw time. The presence of adrenaline in local anesthetics affects blood perfusion, and may thus also affect the thaw time. The aim of the present study was to use IR thermography to monitor the tissue temperature during cryosurgery of actinic keratosis, and to assess the effect of adrenaline in local anesthetics.
Methods
Twelve patients with actinic keratosis in the periorbital region underwent cryosurgery. The temperature was continuously mapped using a high-precision IR camera and was also visually assessed by the surgeon. The results obtained when employing local anesthetics with and without adrenaline were compared.
Results
The temperature change during thawing showed a triphasic pattern. The thaw time was significantly longer when using an anesthetic with adrenaline. This was observed with both IR thermography and by visual observation.
Conclusions
The findings indicate that a longer freezing time may be needed when using a local anesthetic without adrenaline to achieve the same cryo-effect as when using a local anesthetic with adrenaline. A larger clinical trial is needed on the effects of using local anesthetics with and without adrenaline to treat actinic keratosis, for example, the clearance rate, before recommendations can be made concerning their use.
Methods
Twelve patients with actinic keratosis in the periorbital region underwent cryosurgery. The temperature was continuously mapped using a high-precision IR camera and was also visually assessed by the surgeon. The results obtained when employing local anesthetics with and without adrenaline were compared.
Results
The temperature change during thawing showed a triphasic pattern. The thaw time was significantly longer when using an anesthetic with adrenaline. This was observed with both IR thermography and by visual observation.
Conclusions
The findings indicate that a longer freezing time may be needed when using a local anesthetic without adrenaline to achieve the same cryo-effect as when using a local anesthetic with adrenaline. A larger clinical trial is needed on the effects of using local anesthetics with and without adrenaline to treat actinic keratosis, for example, the clearance rate, before recommendations can be made concerning their use.
Department/s
- LTH Profile Area: Engineering Health
- LU Profile Area: Light and Materials
- LTH Profile Area: Photon Science and Technology
- Ophthalmology Imaging Research Group
- Clinical and experimental lung transplantation
- NPWT technology
Publishing year
2025
Language
English
Pages
171-177
Publication/Series
Orbit (London)
Volume
44
Issue
2
Document type
Journal article
Publisher
Taylor & Francis
Topic
- Anesthesiology and Intensive Care
Status
Published
Research group
- Ophthalmology Imaging Research Group
- Clinical and experimental lung transplantation
- NPWT technology
ISBN/ISSN/Other
- ISSN: 0167-6830