
Tobias Erlöv
Researcher

Regional motion correction for in vivo photoacoustic imaging in humans using interleaved ultrasound images
Author
Summary, in Swedish
In translation from preclinical to clinical studies using photoacoustic imaging, motion artifacts represent a major issue. In this study the feasibility of an in-house algorithm, referred to as intensity phase tracking (IPT), for regional motion correction of in vivo human photoacoustic (PA) images was demonstrated. The algorithm converts intensity to phase-information and performs 2D phase-tracking on interleaved ultrasound images. The radial artery in eight healthy volunteers was imaged using an ultra-high frequency photoacoustic system. PA images were motion corrected and evaluated based on PA image similarities. Both controlled measurements using a computerized stepping motor and free-hand measurements were evaluated. The results of the controlled measurements show that the tracking corresponded to 97 ± 6% of the actual movement. Overall, the mean square error between PA images decreased by 52 ± 15% and by 43 ± 19% when correcting for controlled- and free-hand induced motions, respectively. The results show that the proposed algorithm could be used for motion correction in photoacoustic imaging in humans.
Department/s
- Department of Biomedical Engineering
- Ophthalmology Imaging Research Group
- Ophthalmology, Lund
Publishing year
2021-05-12
Language
Swedish
Pages
3312-3322
Publication/Series
Biomedical Optics Express
Volume
12
Issue
6
Links
Document type
Journal article
Publisher
Optical Society of America
Topic
- Radiology, Nuclear Medicine and Medical Imaging
- Ophthalmology
Keywords
- Image quality
- In vivo imaging
- Optical flow
- Photoacoustic imaging
- Spatial resolution
- Spectral imaging
Status
Published
Research group
- Ophthalmology Imaging Research Group
ISBN/ISSN/Other
- ISSN: 2156-7085