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Tobias Erlöv, MSc, PhD. Photo.

Tobias Erlöv

Researcher

Tobias Erlöv, MSc, PhD. Photo.

Comparison of the multi-phasic longitudinal displacement of the left and right common carotid artery in healthy humans

Author

  • Yuxiang Zhu
  • Magnus Cinthio
  • Tobias Erlöv
  • Niclas Bjarnegård
  • Åsa Rydén Ahlgren

Summary, in English

During the cardiac cycle, there is a multi-phasic bidirectional longitudinal movement (LMov) of the intima-media complex of large arteries, i.e. along the arteries. On the left side the common carotid artery (CCA) arises directly from the aortic arc, whereas on the right side the CCA originate from the innominate artery. The aim of this study was to compare LMov of the left and right CCA of healthy subjects to investigate whether the difference in anatomy are of importance for LMov. The CCA's of 93 healthy subjects were investigated using in-house developed ultrasound methods. Although the basic pattern were the same in the majority of subjects, several phases of LMov were significantly larger on the left side (the first retrograde phase, p=00006; the second antegrade, "returning" phase, p<0.00001; and the rapid retrograde phase of movement at the end of the cardiac cycle, p<0.000001). In contrast, no significant side-difference in the amplitude of the first antegrade movement was seen. The maximal (peak-to-peak) LMov was significantly larger on the left side (p=0.002). The side differences found seem to increase with aging, and may be related to the difference in anatomy, including possible difference in distance to the heart and especially the presence of an extra bifurcation on the right side. Our data provide an important base for the further study of the relation between the longitudinal movement and atherosclerosis and atherosclerotic plaques.

Department/s

  • Department of Biomedical Engineering
  • Clinical Physiology and Nuclear Medicine, Malmö
  • Department of Translational Medicine

Publishing year

2021-07-01

Language

English

Pages

342-354

Publication/Series

Clinical Physiology and Functional Imaging

Volume

41

Issue

4

Document type

Journal article

Publisher

John Wiley & Sons Inc.

Topic

  • Medical Biotechnology

Keywords

  • longitudinal motion
  • diameter change
  • axial displacement
  • arterial wall
  • ultrasound

Status

Published

Research group

  • Clinical Physiology and Nuclear Medicine, Malmö

ISBN/ISSN/Other

  • ISSN: 1475-0961