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Sophia Zackrisson, MD, PhD. Photo.

Sophia Zackrisson

Manager

Sophia Zackrisson, MD, PhD. Photo.

The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography

Author

  • Magnus Dustler
  • Daniel Förnvik
  • Pontus Timberg
  • Hannie Petersson
  • Anders Tingberg
  • Sophia Zackrisson

Editor

  • Anders Tingberg
  • Kristina Lång
  • Pontus Timberg

Summary, in English

Breast cancer is diagnosed by a combination of modalities. Measuring the elasto-mechanical properties of suspicious lesions, by e.g. ultrasound elastography, can help differentiate malignant from benign findings. Using a prototype Mechanical Imaging (MI) system as an adjunct to mammography, the aim of this study was to characterize tumors using MI and compare the readings to those from the contralateral breast. Thirteen bilateral MI sets from women with malignant breast lesions were included in this study, drawn from a larger set of 155 women recalled from screening. The results showed that mean lesion pressure was significantly greater than the mean pressure of the corresponding breast, 7.5 ± 7.0 kPa compared to 2.5 ± 1.6 kPa (P = 0.01). There was no evidence for a difference in mean pressure or standard deviation of the MI image between symptomatic and contralateral asymptomatic breasts (P = 0.24 and 0.68). The results support that it is possible to use MI to distinguish malignant cancers from normal breast tissue. Still, further investigations of the characteristics of benign lesions are necessary to ascertain the usefulness of the system.

Department/s

  • Medical Radiation Physics, Malmö
  • BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation

Publishing year

2016

Language

English

Pages

282-288

Publication/Series

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

Volume

9699

Document type

Conference paper

Publisher

Springer

Topic

  • Radiology, Nuclear Medicine and Medical Imaging

Keywords

  • Elastography
  • Mammography
  • Mechanical imaging
  • Screening

Conference name

13th International Workshop on Breast Imaging, IWDM 2016

Conference date

2016-06-19 - 2016-06-22

Conference place

Malmo, Sweden

Status

Published

Research group

  • Medical Radiation Physics, Malmö

ISBN/ISSN/Other

  • ISSN: 16113349
  • ISSN: 03029743
  • ISBN: 978-3-319-41546-8
  • ISBN: 9783319415451