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Professor Malin Malmsjö, MD, PhD. Photo.

Malin Malmsjö

Professor

Professor Malin Malmsjö, MD, PhD. Photo.

Hemodynamic effects of vacuum-assisted closure therapy in cardiac surgery: assessment using magnetic resonance imaging.

Author

  • Rainer Petzina
  • Martin Ugander
  • Lotta Gustafsson
  • Henrik Engblom
  • Johan Sjögren
  • Roland Hetzer
  • Richard Ingemansson
  • Håkan Arheden
  • Malin Malmsjö

Summary, in English

Objective: The hemodynamic effects of vacuum-assisted closure therapy in cardiac surgery are debated. The aim of the present study was to quantify cardiac output and left ventricular chamber volumes after vacuum-assisted closure using magnetic resonance imaging, which is known to be the most accurate method for quantifying these measures. Methods: Six pigs had median sternotomy followed by vacuum-assisted closure treatment in the presence and absence of a paraffin gauze interface dressing. Cardiac output and stroke volume were examined using magnetic resonance imaging flow quantification (breath-hold and real-time). Chamber volumes were assessed using cine magnetic resonance imaging. Results: Cardiac output and stroke volume decreased immediately after application of negative pressures of 75, 125, and 175 mm Hg (13% +/- 1% decrease in cardiac output). Interposition of 4 layers of paraffin gauze dressing over the heart during vacuum-assisted closure therapy resulted in a smaller decrease in cardiac output (8% +/- 1%). Conclusions: Vacuum-assisted closure therapy results in an immediate decrease in cardiac output, although to a lesser extent than shown previously. Covering the heart with a wound interface dressing lessens the hemodynamic effects of vacuum-assisted closure.

Department/s

  • Medicine, Lund
  • Clinical Physiology (Lund)
  • Division of Microbiology, Immunology and Glycobiology - MIG
  • Thoracic Surgery
  • Lund Cardiac MR Group

Publishing year

2007

Language

English

Pages

1154-1162

Publication/Series

Journal of Thoracic and Cardiovascular Surgery

Volume

133

Issue

5

Document type

Journal article

Publisher

Mosby-Elsevier

Topic

  • Cardiac and Cardiovascular Systems
  • Surgery

Status

Published

Research group

  • Lund Cardiac MR Group

ISBN/ISSN/Other

  • ISSN: 1097-685X