Malin Malmsjö
Professor
Hemodynamic effects of vacuum-assisted closure therapy in cardiac surgery: assessment using magnetic resonance imaging.
Author
Summary, in English
Objective: The hemodynamic effects of vacuum-assisted closure therapy in cardiac surgery are debated. The aim of the present study was to quantify cardiac output and left ventricular chamber volumes after vacuum-assisted closure using magnetic resonance imaging, which is known to be the most accurate method for quantifying these measures. Methods: Six pigs had median sternotomy followed by vacuum-assisted closure treatment in the presence and absence of a paraffin gauze interface dressing. Cardiac output and stroke volume were examined using magnetic resonance imaging flow quantification (breath-hold and real-time). Chamber volumes were assessed using cine magnetic resonance imaging. Results: Cardiac output and stroke volume decreased immediately after application of negative pressures of 75, 125, and 175 mm Hg (13% +/- 1% decrease in cardiac output). Interposition of 4 layers of paraffin gauze dressing over the heart during vacuum-assisted closure therapy resulted in a smaller decrease in cardiac output (8% +/- 1%). Conclusions: Vacuum-assisted closure therapy results in an immediate decrease in cardiac output, although to a lesser extent than shown previously. Covering the heart with a wound interface dressing lessens the hemodynamic effects of vacuum-assisted closure.
Department/s
- Medicine, Lund
- Clinical Physiology (Lund)
- Division of Microbiology, Immunology and Glycobiology - MIG
- Thoracic Surgery
- Lund Cardiac MR Group
Publishing year
2007
Language
English
Pages
1154-1162
Publication/Series
Journal of Thoracic and Cardiovascular Surgery
Volume
133
Issue
5
Links
Document type
Journal article
Publisher
Mosby-Elsevier
Topic
- Cardiac and Cardiovascular Systems
- Surgery
Status
Published
Research group
- Lund Cardiac MR Group
ISBN/ISSN/Other
- ISSN: 1097-685X