
Malin Malmsjö
Professor

Increased ET(A) and ET(B) receptor contraction in the left internal mammary artery from patients with hypertension.
Author
Summary, in English
Patients with hypertension have an increased activity in the endothelin system and an increased vascular tone, which predisposes them to target organ damage. In the present study, in vitro pharmacology, real-time PCR and immunofluorescence techniques were used to show enhanced endothelin type A (ETA) and type B (ETB) receptor contraction and expression in the left internal mammary artery from patients with hypertension as compared to normotensive patients. These receptors may be important in the pathophysiology of hypertension.
Department/s
- Medicine/Emergency Medicine, Lund
- Ophthalmology, Lund
- Thoracic Surgery
Publishing year
2008
Language
English
Pages
226-229
Publication/Series
Journal of Human Hypertension
Volume
22
Issue
3
Links
Document type
Journal article
Publisher
Nature Publishing Group
Topic
- Cardiac and Cardiovascular Systems
Status
Published
ISBN/ISSN/Other
- ISSN: 1476-5527