Malin Malmsjö
Professor
Mechanisms governing the effects of vacuum-assisted closure in cardiac surgery
Author
Summary, in English
Vacuum-assisted closure has been adopted as the first-line treatment for poststernotomy mediastinitis as a result of the excellent clinical outcome achieved with its use. Scientific evidence regarding the mechanisms by which vacuum-assisted closure promotes wound healing has started to emerge, although knowledge regarding the effects on heart and lung function is still limited. The organs in the mediastinum are hemodynamically crucial, and in patients with poststernotomy mediastinitis, vulnerable bypass grafts and reduced cardiac function must be taken into consideration during vacuum-assisted closure therapy. This article provides an overview of the effects of vacuum-assisted closure on heart and lung function and summarizes the current knowledge on the mechanisms by which vacuum-assisted closure therapy promotes wound healing.
Department/s
- Medicine, Lund
- Thoracic Surgery
Publishing year
2007
Language
English
Pages
1266-1275
Publication/Series
Plastic and Reconstructive Surgery
Volume
120
Issue
5
Links
Document type
Journal article
Publisher
Lippincott Williams & Wilkins
Topic
- Surgery
Status
Published
ISBN/ISSN/Other
- ISSN: 0032-1052