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Magnus Cinthio, MSc, PhD. Photo.

Magnus Cinthio

Senior lecturer

Magnus Cinthio, MSc, PhD. Photo.

An automatic method for measurements of arterial intima-media thickness using ultrasonic B-mode data

Author

  • Magnus Cinthio
  • Åsa Rydén Ahlgren
  • Tomas Jansson
  • Tobias Erlöv
  • Hans W Persson
  • Kjell Lindström

Summary, in English

We have previously developed algorithms that use B-mode cineloops for simultaneous measurements of arterial diameter change and longitudinal movement of the arterial wall. In this study the lumen diameter algorithm was extended to also measure arterial intima-media thickness of the far wall. To optimize the algorithm the influence of the lateral width of the region-of-interest (1 pixel, 0.1 mm, 0.5 mm, 1 mm, 2.5 mm and 5 mm) was evaluated. The algorithm estimated intima-media thickness at diastole automatically by measuring the distance between the two positions where the laterally averaged B-mode intensity envelope crosses a threshold value relative to the maximum amplitudes of the intimal and adventitial echoes, respectively. The sub-pixel resolution is achieved by solving the equation of a straight line between the two samples on either side of the threshold value. The measurements were performed on 20 healthy normotensive volunteers (age 25–57 years) on the common carotid artery 2–3 cm proximal to the bifurcation. For the 2.5-mm width, which was considered the best, the intima-media thickness was mean 646 μm (SD 66) for men and 613 μm (SD 68) for women. The systematic difference was −5 μm and the random difference was 31 μm. The CV was 4.9%. The study indicates that the reproducibility is sufficient for in vivo studies when the width of the region-of-interest is 1.0 mm or wider.

Department/s

  • Department of Biomedical Engineering
  • Clinical Physiology and Nuclear Medicine, Malmö
  • Department of Biomedical Engineering

Publishing year

2012

Language

English

Pages

115-122

Publication/Series

Acoustical Imaging

Volume

31

Document type

Conference paper

Publisher

Springer

Topic

  • Medical Image Processing

Conference name

31st International Symposium on Acoustical Imaging

Conference date

2011-04-10 - 2011-04-13

Conference place

Warsaw, Poland

Status

Published

Research group

  • Clinical Physiology, Malmö

ISBN/ISSN/Other

  • ISBN: 978-94-007-2619-2
  • ISBN: 978-94-007-2618-5