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Associate Professor Magnus Cinthio, MSc, PhD. Photo.

Magnus Cinthio

Professor

Associate Professor Magnus Cinthio, MSc, PhD. Photo.

Hemoglobin induces inflammation after preterm intraventricular hemorrhage by methemoglobin formation.

Author

  • Magnus Gram
  • Snjolaug Sveinsdottir
  • Karsten Ruscher
  • Stefan Hansson
  • Magnus Cinthio
  • Bo Åkerström
  • David Ley

Summary, in English

Cerebral intraventricular hemorrhage (IVH) is a major cause of severe neurodevelopmental impairment in preterm infants. To date, no therapy is available that prevents infants from developing serious neurological disability following IVH. Thus, to develop treatment strategies for IVH, it is essential to characterize the initial sequence of molecular events that leads to brain damage. In this study, we investigated extracellular hemoglobin (Hb) as a causal initiator of inflammation in preterm IVH.

Department/s

  • Infection Medicine (BMC)
  • Paediatrics (Lund)
  • Neurosurgery
  • Obstetrics and Gynaecology (Lund)
  • Division for Biomedical Engineering
  • Redox Medicine
  • MultiPark: Multidisciplinary research on neurodegenerative diseases

Publishing year

2013

Language

English

Publication/Series

Journal of Neuroinflammation

Volume

10

Issue

Aug.,6

Full text

Document type

Article

Publisher

BioMed Central (BMC)

Topic

  • Neurology

Status

Published

Research group

  • Redox Medicine

ISBN/ISSN/Other

  • ISSN: 1742-2094