Gustav Smith
Associate professor
Ceruloplasmin and atrial fibrillation: evidence of causality from a population-based Mendelian randomization study.
Author
Summary, in English
Inflammatory diseases and inflammatory markers secreted by the liver, including C-reactive protein (CRP) and ceruloplasmin, have been associated with incident atrial fibrillation (AF). Genetic studies have not supported a causal relationship between CRP and AF, but the relationship between ceruloplasmin and AF has not been studied. The purpose of this Mendelian randomization study was to explore whether genetic polymorphisms in the gene encoding ceruloplasmin are associated with elevated ceruloplasmin levels, and whether such genetic polymorphisms are also associated with the incidence of AF.
Department/s
- Cardiovascular Research - Epidemiology
- Cardiovascular Research - Hypertension
- Cardiology
- Internal Medicine - Epidemiology
- EXODIAB: Excellence of Diabetes Research in Sweden
- EpiHealth: Epidemiology for Health
Publishing year
2014
Language
English
Pages
164-171
Publication/Series
Journal of Internal Medicine
Volume
275
Issue
2
Links
Document type
Journal article
Publisher
Wiley-Blackwell
Topic
- Cardiac and Cardiovascular Systems
Status
Published
Research group
- Cardiovascular Research - Epidemiology
- Cardiovascular Research - Hypertension
- Internal Medicine - Epidemiology
ISBN/ISSN/Other
- ISSN: 1365-2796