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Nils Gustafsson. Photo.

Nils Gustafsson

Postdoctoral fellow

Nils Gustafsson. Photo.

Walking by design : how to build artificial molecular motors made of proteins

Author

  • Patrik F. Nilsson
  • Anna Zink
  • Olivier M.C. Laprévote
  • Chapin S. Korosec
  • Nils Gustafsson
  • Neil O. Robertson
  • Nancy R. Forde
  • Ralf Eichhorn
  • Birte Höcker
  • Paul M.G. Curmi
  • Heiner Linke

Summary, in English

To design an artificial protein-based molecular motor that can autonomously step along a track is a key challenge of protein design and synthetic biology. We lay out a roadmap for how to achieve this aim, based on a modular approach that combines the use of natural, non-motor proteins with de novo design. We define what can be considered to constitute a successful artificial protein motor, identify key steps along the path to achieve these designs, and provide a vision for the future beyond this aim.

Department/s

  • Solid State Physics
  • Physical Chemistry
  • Division of Translational Cancer Research
  • NanoLund: Centre for Nanoscience
  • LTH Profile Area: Nanoscience and Semiconductor Technology
  • LU Profile Area: Light and Materials
  • Ophthalmology Imaging Research Group
  • LTH Profile Area: Engineering Health

Publishing year

2024

Language

English

Publication/Series

Nano Futures

Volume

8

Issue

4

Document type

Article

Publisher

IOP Publishing

Topic

  • Condensed Matter Physics (including Material Physics, Nano Physics)

Keywords

  • molecular motors
  • nanotechnology
  • protein design
  • proteins
  • synthetic biology

Status

Published

Research group

  • Ophthalmology Imaging Research Group

ISBN/ISSN/Other

  • ISSN: 2399-1984